Medical and Health

Cannabidiol (CBD) oil comes from the Cannabis plant and has become a popular alternative therapy for a range of conditions over the past few years. People report using CBD oil to help reduce pain, anxiety, and sleep disorders.

Due to the prohibition of cannabis and associated research restrictions, there are limited evidence from human studies to support the benefits of CBD oil. However, with the legalization of cannabis in some regions around the globe, research in this area is gaining momentum.

CBD is just one of many different molecules unique to the Cannabis plant. CBD oil generally contains low levels of the cannabinoid tetrahydrocannabinol (THC), which is the compound that produces the ‚Äėhigh.‚Äô

People report using CBD oil for a variety of medical conditions without experiencing the intoxicating effects of THC. Generally, most people tolerate CBD is well and experience minimal serious side effects.

Unlike THC, CBD does not bind readily to cannabinoid receptors. These receptors are key components of the human endocannabinoid system, which plays a crucial role in the central nervous system.

Endocannabinoids are signaling molecules that help regulate various processes, such as pain, memory, mood, immunity, and stress.

CBD does, however, interact with other receptors, such as serotonin and opioid receptors. It might also boost levels of naturally occurring endocannabinoids, which may explain its seemingly broad range of uses.

Keep reading to learn about some of the possible benefits of using CBD oil.

A review of completed and ongoing clinical trials indicated that adding CBD to common antiepileptic drugs may be appropriate in treatment-resistant epilepsy in infants, children, and teenagers.

1. Epilepsy.

The first CBD-based medication that the Food and Drug Administration (FDA) approved was Epidiolex. Doctors prescribe Epidiolex to those who experience seizures due to Lennox-Gastrault or Dravet syndrome, which are rare types of epilepsy.

Epidiolex underwent rigorous human studies before the FDA approved it as a treatment for these two conditions.

According to an article in Molecules, scientists do not know precisely how CBD helps control seizures. One theory suggests that CBD influences a receptor involved in seizure activity called transient receptor potential vanilloid.

A review of completed and ongoing clinical trials indicated that adding CBD to common antiepileptic drugs may be appropriate in treatment-resistant epilepsy in infants, children, and teenagers.

2. Pain and inflammation

Researchers have investigated the pain-relieving effects of CBD. A small 2020 randomized, placebo-controlled trial investigated the use of topical CBD oil on people with peripheral neuropathy of the legs.

In this small study, participants with peripheral noncancer neuropathic pain received either 250 milligrams (mg) of CBD total dissolved in 3 oz of oil) or a placebo.

After 4 weeks, the researchers noted a statistically significant reduction in intense pain, sharp pain, cold and itchy sensations in those using CBD oil. Participants did not report any side effects.

Although the results of this small trial are positive, it involved just 29 participants, so researchers need to conduct more investigations to confirm the results.

Another study review demonstrated that a 1:1 combination of THC and CBD sprayed in the back of the mouth (a pharmaceutical product called Sativex) might be effective for noncancer related chronic pain.

However, the researchers do not know which of the two compounds had the most significant effect. Also, the follow-up period for this study was 15 weeks. Scientists must carry out further research to confirm whether long-term pain control is possible.

This spray that contained both THC and CBD may also have anti-inflammatory properties. An earlier study on people living with rheumatoid arthritis showed that Sativex reduced the Disease Activity Score-28, which demonstrates a decrease in inflammation.

These studies show the potential effectiveness of CBD on pain and inflammation.

Learn more about CBD for pain here.

3. Depression and anxiety

Many animal studies on the effects of CBD on mood disorders showed promising results. An earlier article in Neuropsychopharmacology outlined a study on humans where researchers demonstrated that CBD could reduce anxiety caused by public speaking.

The participants took a CBD preparation before a public-speaking event. They reported feeling less anxiety and discomfort. Researchers suggest that CBD may help relieve anxiety associated with the anticipation of a fearful event.

The participants also had lower negative self-evaluation during public speaking. Researchers suggest that serotonin receptors may play a role in the effects of CBD on anxiety.

Human studies on the effectiveness of CBD on depression are currently lacking. It is necessary to carry out further research before using it for this purpose.

Learn more about CBD for depression here.

Learn more about CBD for anxiety here.

4. Addiction management and treatment

Some experts suggest that CBD oil can help people with addiction by reducing activation of the amygdala, a brain area involved in addiction.

Cravings for drugs generally occur by exposure to a particular cue. So, reducing the craving during cues can help people abstain from heroin.

A study published in the American Journal of Psychiatry explored CBD’s effect on cue-inducing craving and anxiety in people with heroin use disorder. The researchers demonstrated that compared with placebo, those who took CBD had lower cravings and anxiety. These results are promising and require further investigation.

5. Inflammatory skin conditions

In some studies, certain cannabinoids demonstrate anti-inflammatory, anti-itch, anti-aging, and anticancer properties. Some experts suggest that these effects occur when the drug interacts with the endocannabinoid system found on the skin.

Some skin conditions that may improve with CBD treatment include:

Cell studies demonstrated that CBD prevented some of the functions of the sebaceous glands that contribute to acne. Researchers need to confirm these results in human studies before doctors can recommend their use.

6. Neuroprotection

An article in Molecules indicates that animal studies have shown that CBD might offer neuroprotective activity in several neurodegenerative diseases, including:

Researchers suggest that the neuroprotective effects occur from the anti-inflammatory and antioxidant properties of CBD.

In some countries, doctors can prescribe Sativex, a drug that contains THC and CBD, to relieve spasticity in people with MS. Scientists are not sure how it works.

7. Relief from chemotherapy side effects

An article in the British Journal of Pharmacology indicates that the effect of CBD on nausea and vomiting in animals may have links to its interaction with the serotonin receptors. However, the article concludes that THC appears to have a greater ability to reduce nausea and vomiting than CBD.

In one human study, people with nausea and vomiting induced by chemotherapy experienced relief when taking Sativex, but it is unclear how much of a contribution the CBD provided. Further review is necessary to understand the role of CBD in relieving nausea and vomiting.

Learn more about CBD for cancer here.

Other forms of CBD

CBD oil is not the only form of CBD that people use for medicinal purposes. Different types of CBD include:

  • capsules
  • creams & salves
  • high-CBD flower for inhalation
  • edibles (such as gummies)
  • drinks

The effect that a person may get from using CBD may differ according to whether they are inhaling it or taking it orally. Side effects of CBD may also vary depending on the form consumed.

Learn about the top available CBD oils here.

Learn about the top CBD gummies here.

Summary

People use CBD oil and other CBD-based products for different reasons, including reducing pain, controlling anxiety, and managing seizures.

Although studies report few side effects with CBD use, its effectiveness for various medical conditions requires further research.

Other people use CBD oil for medical conditions that researchers have not rigorously studied yet. People who use CBD oil should speak with a doctor to ensure the drug is safe and whether CBD is more effective than other conventional medications.

5 Things You Didn’t Know About Medical

With all the hype surrounding CBD, there’s plenty of information to be had on the compound. Derived from hemp, CBD is one of 113 cannabinoids found in cannabis. Each cannabinoid interacts with our body in a specific way, and we even have specialised receptors in our nervous system to accept them.

As research continues to grow, so too does the demand for CBD products. So much so, in fact, that the market has yielded some impressive profits in the two years since the Farm Bill was passed; which effectively legalised hemp and CBD at the federal level.

Whatever you might know about CBD, there’s a good chance you don’t know these five facts. Keep reading to learn what they are, they might just surprise you.

1. It’s One Of The Fastest-Growing Industries In History: You can buy pharmaceutical grade CBD oil in stores and at several online providers all over the country. This massive spread of CBD products is due to the incredible demand for CBD and CBD-based products; causing the industry to become one of the fastest-growing in history.

Financial experts have predicted that the CBD industry has grown at around 107% per-year, and will continue to do so for the better half of the decade. People simply love CBD products, and as researchers discover more amazing benefits, the demand only grows.

The CBD industry managed to surpass the one billion dollar mark last year, and is projected to surpass 10-20 billion in the next few years. As misinformation and stigma dissipate, facts and scientific data take their place, making cannabis, hemp, and CBD better understood by everyone.

2. It Can Help Cancer Patients Manage Symptoms: CBD offers some very promising results in cancer patients. Cancer is a devastating condition where cells divide uncontrollably and destroy tissue. This can include muscle tissue, organs, blood vessels, and more. Often, cancer is incredibly painful, and the treatments available for cancer are no less uncomfortable than the disease itself.

Cannabinoids may actually help with more than just the symptoms of cancer, however. Certain studies have shown that cannabinoids, including CBD, might actually help to slow the growth of tumours. Another study found that it could potentially make cancerous cells more susceptible to radiation while not affecting healthy cells.

Overall, it would seem that CBD has the ability to inhibit cancer growth, manage symptoms, and aid in the destruction of cancerous cells. These are all great things, but further research must be conducted before these benefits can be cemented into CBD’s repertoire.

3. There’s a CBD-Based Drug Available for Seizures: Believe it or not, the FDA itself has recognised and performed research on the effectiveness of CBD in treating certain conditions, and recently approved a drug called Epidiolex, which is formulated from CBD. This breakthrough in CBD research proves that CBD is both useful and effective in medical applications.

Epidiolex is used to treat certain severe forms of epilepsy, such as Dravet Syndrome. These rare conditions can cause debilitating and often dangerous seizures. The CBD-based drug seems to reduce the number of as well as the severity of these seizures, making life more comfortable and manageable for those suffering from these conditions.

4. CBD Is Opening New Doors In Medical Research: Besides treating epilepsy and cancer, CBD is opening doors to all kinds of new research. Studies have been conducted on the compound’s effectiveness at treating or affecting conditions such as anxiety; depression; PTSD; diabetes; heart disease; high blood pressure; skin conditions; Alzheimer’s and more.

According to the Penguin CBD team, now that CBD and hemp are officially legalised, there’s plenty of room for more research and plenty of money in the industry to support new studies. With specialised receptors for cannabinoids in our nervous systems, it’s clear that our bodies are somewhat designed to accept and make use of cannabinoids, and their incredible list of benefits only continues to grow as we learn more.

CBD has yet another useful application: helping to treat addiction. Opioid-based painkillers are the cause of thousands of overdoses and deaths each year, and yet, they’re continuously prescribed without any valid alternatives available. CBD is effective at pain management but has also been shown to reduce the symptoms of withdrawal and help reduce cravings in addicts.

5. CBD Can Be Used In Pets And Children: You probably didn’t know you could give your furry friend CBD, did you? CBD pet treats are available for pets who suffer from chronic pain, inflammation, anxiety, or even have appetite problems. They’re tasty and you’re pet won’t know that they contain anything other than that yummy steak flavour they love so much!

Pet owners all over the country are choosing CBD oil to bring their pets easy comfort and relief from conditions like arthritis. While the research on pets and CBD is scarce, millions of pet owners swear by CBD and its effectiveness.

You can also give CBD to your children. In fact, there are studies available that suggest CBD may be an effective treatment for ADHD instead of giving stimulants to your child. That’s not to say you should immediately replace your child’s ADHD medication with CBD, but you can certainly talk with your child’s doctor about this natural alternative. Many parents have found CBD to be effective at managing hyperactive children and those with focus or concentration issues.

Children also suffer from chronic pain, inflammation, and conditions such as anxiety. CBD is truly an amazing compound with a myriad of useful applications, and it spans beyond just use in adults and humans. Your pets and your children can experience its benefits as well; check out one of the many relevant guides at CBD Fable to discover more.

CBD is only growing in popularity, and you can be sure to see some more amazing benefits discovered as more money and effort go into CBD studies. With CBD’s legal status solidified, it’s not much easier to study its effects and perform clinical trials without the threat of government interference. Where will the future of CBD and CBD products will take us? The road ahead is set to be an exciting one…

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